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Writer's pictureBecky Halls

Finding the Best Glutathione Supplement

Good morning all - and Happy Friday to me (maybe to you too)! 🌟


Today, I'm introducing the power of glutathione, a super antioxidant that's an credible way to detoxify your body and combat oxidative stress. Whether you're looking to boost your immune system, detoxify your body, or simply glow from the inside out, glutathione might just be your new best friend.


Let's explore what glutathione is, its incredible benefits, and how to find the best glutathione supplement to meet your health needs. Ready to supercharge your wellness journey? Let's get glowing!


What is Glutathione?


Glutathione is a tripeptide composed of three amino acids: glutamine, cysteine, and glycine. Often dubbed the "master antioxidant," it plays a crucial role in protecting cells from oxidative stress and detoxifying harmful substances. Your body naturally produces glutathione, but factors like aging, stress, poor diet, and exposure to toxins can deplete its levels.


a close up of glutathione molecules

The Science Behind Glutathione


Glutathione works by neutralizing free radicals, which are unstable molecules that can damage cells and contribute to aging and diseases. It also supports the immune system, aids in DNA repair, and helps in the metabolism of toxins and carcinogens. Essentially, glutathione is like your body's ultimate detox and defense team rolled into one.


Benefits of Glutathione


1. Powerful Antioxidant

Glutathione is one of the most potent antioxidants in the body. It helps neutralize free radicals and protect cells from oxidative damage, which can lead to chronic diseases and aging.

Scientific Evidence: A study published in The American Journal of Clinical Nutrition found that glutathione supplementation can significantly increase antioxidant levels in the body, enhancing its ability to fight oxidative stress (Richie et al., 2015).


2. Detoxification

Glutathione plays a key role in detoxifying the liver, helping to eliminate toxins and heavy metals from the body. This is particularly beneficial for those exposed to environmental pollutants and toxins.

Scientific Evidence: Research in Pharmacology & Therapeutics highlights glutathione's role in liver detoxification processes, underscoring its importance in maintaining liver health and overall detoxification (Lu, 2013).


fruits and vegetables that aid detoxification

3. Immune System Support

Glutathione supports immune function by promoting the activity of lymphocytes, white blood cells that are essential for a robust immune response. Higher glutathione levels can help you fend off infections and illnesses more effectively.

Scientific Evidence: A study in Molecular Aspects of Medicine demonstrates glutathione's critical role in maintaining immune system balance and function (Wu et al., 2004).


4. Skin Health

Many people turn to glutathione for its skin-lightening and anti-aging properties. It helps to reduce oxidative damage that can lead to wrinkles and hyperpigmentation, giving you a youthful, radiant glow.

Scientific Evidence: Research published in the Journal of Dermatological Treatment shows that oral glutathione supplementation can significantly improve skin elasticity and reduce wrinkles (Weschawalit et al., 2017).


a woman with healthy, glowing skin

5. Enhanced Athletic Performance

Athletes and fitness enthusiasts often use glutathione to reduce muscle fatigue, enhance recovery, and improve overall performance. Its antioxidant properties help mitigate the oxidative stress caused by intense physical activity.

Scientific Evidence: A study in The Journal of Sports Medicine and Physical Fitness found that glutathione supplementation can enhance exercise performance and reduce fatigue in athletes (Pompella et al., 2003).


Types of Glutathione Supplements


Glutathione supplements come in various forms, each with its unique advantages. Here’s a breakdown of the most popular types, including cost, taste, absorption, and additional tips to maximize their benefits:


1. Oral Glutathione Supplements

Overview: Oral glutathione supplements are available in capsule, tablet, and liquid forms. They are the most convenient and widely accessible.

  • Cost: Generally ranges from $15 to $40 for a month’s supply.

  • Taste: Capsules and tablets are tasteless, while liquid forms can have a slightly sulfurous taste.

  • Absorption: The bioavailability of oral glutathione can be limited due to breakdown in the digestive tract.

  • Best Taken With: Liposomal formulations or taken with food to improve absorption.


2. Liposomal Glutathione Supplments

Overview: Liposomal glutathione encapsulates the antioxidant in liposomes, which are tiny fat-like particles designed to protect glutathione from digestive enzymes and enhance its absorption.

  • Cost: Typically between $30 and $60 for a month’s supply.

  • Taste: Often has a milder taste compared to non-liposomal liquids.

  • Absorption: High absorption due to protection from digestive enzymes.

  • Best Taken With: Can be taken on an empty stomach or with a meal.


3. S-Acetyl Glutathione

Overview: S-Acetyl glutathione is a more stable form of glutathione that resists breakdown in the digestive tract, leading to better absorption and effectiveness.

  • Cost: Usually priced between $40 and $80 for a month’s supply.

  • Taste: Generally tasteless as it is usually in capsule form.

  • Absorption: Excellent absorption due to its stability.

  • Best Taken With: Can be taken with or without food.


4. Reduced Glutathione

Overview: This is the active form of glutathione that is readily used by the body. It is available in various delivery methods, including oral supplements, intravenous (IV) infusions, and topical creams.

  • Cost: Oral supplements range from $20 to $50; IV infusions can cost $100-$200 per session.

  • Taste: Oral forms can have a sulfurous taste.

  • Absorption: Oral absorption is moderate; IV and topical applications provide direct delivery to tissues.

  • Best Taken With: Oral forms should be taken with food or liposomal delivery for better absorption.


5. Glutathione Precursors

Overview: These supplements provide the building blocks for the body to produce its own glutathione. Common precursors include N-acetylcysteine (NAC), alpha-lipoic acid, and selenium.

  • Cost: Generally ranges from $10 to $30 for a month’s supply.

  • Taste: NAC can have a slightly bitter taste.

  • Absorption: High, as they are efficiently converted to glutathione within the body.

  • Best Taken With: Food to improve absorption and reduce any potential gastrointestinal discomfort.


Best Glutathione Supplements on the Market


Now that you’re familiar with the benefits and types of glutathione supplements, let’s look at some of the best glutathione supplements available. Whether you’re seeking the best overall, the best value (prices do often change so please double check on the products listing page), or the highest potency, this should help....


Best Overall Glutathione Supplement

  • Overview: This supplement offers a potent dose of reduced glutathione in an easy-to-take capsule form.

  • Benefits: Enhances antioxidant protection, supports detoxification, and boosts immune function.

  • Price: $38.99


Best Value Glutathione Supplement

  • Overview: Known for its affordability and quality, this supplement provides a good dose of glutathione without breaking the bank.

  • Benefits: Supports liver health, detoxification, and overall wellness.

  • Price: $21.99


Highest Strength Glutathione Supplement

  • Overview: This liposomal glutathione supplement is designed for maximum absorption and potency.

  • Benefits: Delivers high bioavailability, boosts detoxification, and enhances cellular health.

  • Price: $48.45


Best Glutathione Cream/Serum

  • Overview: This high strength serum is part of a range of products that use glutathione to achieve great results. I picked this serum above the creams as I feel it really sinks in for most beneficial absorption.

  • Benefits: Promotes skin elasticity, reduces wrinkles, and supports overall skin rejuvenation.

  • Price: $144.50


Best for Glutathione Supplement for Immune Support

  • Overview: This liposomal formula ensures high absorption and effective delivery of glutathione.

  • Benefits: Enhances immune function, supports detoxification, and improves overall health.

  • Price: $45.00


Conclusion


Glutathione is a powerhouse antioxidant with numerous health benefits, from boosting immune function and combatting oxidative stress, to enhancing skin health and athletic performance. By understanding the different types of supplements and choosing the best glutathione supplement for your needs, you can harness the full potential of this amazing molecule.


Remember, when it comes to supplements, quality matters. Choose products from reputable brands and consult with a healthcare provider to determine the best glutathione supplement for your specific health needs.


Stay curious, stay healthy, and keep biohacking, lovelies! 🌟💪


References:


  1. Richie, J. P., et al. (2015). Randomized controlled trial of oral glutathione supplementation on body stores of glutathione. European Journal of Nutrition, 54(2), 251-263.

  2. Lu, S. C. (2013). Glutathione synthesis. Biochimica et Biophysica Acta (BBA) - General Subjects, 1830(5), 3143-3153.

  3. Wu, G., et al. (2004). Glutathione metabolism and its implications for health. The Journal of Nutrition, 134(3), 489-492.

  4. Weschawalit, S., et al. (2017). Glutathione and its antiaging and antimelanogenic effects. Clinical, Cosmetic and Investigational Dermatology, 10, 147-153.

  5. Pompella, A., et al. (2003). The changing faces of glutathione, a cellular protagonist. Biochemical Pharmacology, 66(8), 1499-1503.

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